Cardiff Blues and Ospreys clash at the BT Sport Arms Park for the first time in three years as they look to kickstart their Anglo-Welsh Cup campaigns.

Both sides were beaten by experienced English opposition in their first outings, and will be out to bounce back against their regional rivals. This weekend's hosts, who had an average age of just 20-years-old in round one, were hammered 62-25 by Exeter at Sandy Park.

It was a lot closer in Swansea as the Ospreys returned to St. Helens to take-on Adam Jones' Harlequins. The young Ospreys surged into the lead but eventually broke against a string Quins pack to go down 15-12. And both sides are aiming to bounce back against their rivals.

Blues coach Richard Hodges said: "We've gone through the lessons that need to be learned from last week's game in detail and they need to be applied against the Ospreys on Friday night.

"With the Principality Stadium double-headers, we usually play against the Ospreys there. But we have the opportunity to play them at our place on a dry night with little wind, which should lend itself to a big occasion. We want to have a good crack at them in a welsh derby, that should stoke the fires of the players, and we should be an energised group come Friday."

Ospreys coach Tom Smith said: "There was a lot of frustration around the result last week, but we have to look at what this competition is all about which is giving youngsters an opportunity to show what they have got. Some of the boys did credit to themselves.

"If we perform well then the outcome will take care of itself. We want to win, we're a competitive bunch and we were bitterly disappointed to lose out last Friday. The Blues are going to turn up knowing that it is a Welsh derby, we are not taking their last result as what they are capable of."